Do NOT use Combivent Aerosol if:

• you are allergic to any ingredient in Combivent Aerosol, to atropine, or to similar medicines
• you are allergic to soya lecithin or related foods, such as soybean.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Combivent Aerosol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances (including peanuts)
• if you have a history of heart problems, (eg, fast or irregular heartbeat, chest pain, low blood output), blood vessel problems, high blood pressure, or low blood potassium levels
• if you have a history of other lung or breathing problems (eg, asthma, hyperactive airway)
• if you have a history of an overactive thyroid, diabetes, seizures, liver or kidney problems, or an adrenal gland tumor (pheochromocytoma)
• if you have a history of an enlarged prostate, blockage or narrowing of the bladder, or glaucoma
• if you have had an unusual reaction to other sympathomimetic medicines (eg, pseudoephedrine)
• if you are taking a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) or tricyclic antidepressant (eg, amitriptyline), or you have taken either of these medicines within the last 14 days.

Some medicines may interact with Combivent Aerosol. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood potassium levels may be increased
• Anticholinergics (eg, bromocriptine, methscopolamine), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), MAOIs (eg, phenelzine), sympathomimetics (eg, pseudoephedrine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Combivent Aerosol's side effects
• Beta-blockers (eg, propranolol) because they may decrease Combivent Aerosol's effectiveness.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Combivent Aerosol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

• Combivent Aerosol is for use in the mouth only. Do not get Combivent Aerosol in your eyes. Getting it in your eyes may cause eye pain, redness, irritation, or discomfort; blurred vision or other vision changes; or worsening of narrow-angle glaucoma. If you get Combivent Aerosol in your eyes, rinse immediately with cool tap water. Check with your doctor if you develop any of these effects.
• Combivent Aerosol may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you use it with alcohol or certain medicines. Use Combivent Aerosol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not take more than the recommended dose without checking with your doctor. The risk of severe heart problems and sometimes death may be increased with overuse of Combivent Aerosol.
• If Combivent Aerosol stops working well, if your symptoms become worse, or if you need to use Combivent Aerosol more often than usual, contact your doctor right away.
• Combivent Aerosol may cause dry mouth or unpleasant taste in your mouth. To prevent dry mouth, rinse your mouth and gargle after using Combivent Aerosol. If you experience dry mouth, use sugarless gum or candy, or melt bits of ice in your mouth. If you have any of these problems, ask your health care provider if a spacing device may help.
• Combivent Aerosol may sometimes cause severe breathing problems right after you use a dose. When this problem occurs, it is often after the first use of a new canister. If this happens, seek medical care at once.
• Tell your doctor or dentist that you take Combivent Aerosol before you receive any medical or dental care, emergency care, or surgery.
• Check with your doctor before using any other inhaled medicines while you are using Combivent Aerosol.
• Carry an ID card at all times that says you use Combivent Aerosol.
• Lab tests, including lung function tests, blood pressure, or potassium blood levels may be performed while you use Combivent Aerosol. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• The contents of Combivent Aerosol are under pressure. Store away from heat and direct sunlight. Do not puncture, break, or burn the canister even if it appears to be empty.
• Combivent Aerosol should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
• Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Combivent Aerosol while you are pregnant. It is not known if Combivent Aerosol is found in breast milk. Do not breastfeed while using Combivent Aerosol.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Coughing; dizziness; dry mouth; headache; nausea; nervousness; sinus inflammation; sore throat; trouble sleeping; unusual taste in mouth.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; clammy skin; difficulty urinating; fast or irregular heartbeat; new or worsening breathing problems; numbness of an arm or leg; pain, tightness, or pressure in the jaw, neck, or chest; pounding in the chest; severe headache, nausea, vomiting, or dizziness; severe stomach pain; shortness of breath; swelling of the arms or legs; tremors; vision changes; wheezing.

 This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.